求助Review of lamotrigine and its clinical applications in epi
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求助Review of lamotrigine and its clinical applications in epilepsy.全文.(急呀)
西南大学、深圳大学、北大图书馆数据库里有全文。这几个学校的同学帮下忙呀!
西南大学、深圳大学、北大图书馆数据库里有全文。这几个学校的同学帮下忙呀!
Abstract
Lamotrigine is an anti-epileptic agent with broad efficacy.Lamotrigine works at voltage-sensitive sodium channels,thereby stabilising the neuronal membrane and inhibiting the release of excitatory neurotransmitters such as glutamate and aspartate.Early preclinical animal studies indicate its broad-spectrum efficacy,which was later confirmed in clinical trials.Multiple randomised,placebo-controlled and comparative trials demonstrate its efficacy against partial and secondarily generalised seizures.Open-label trials show its efficacy against generalised seizures,especially absence seizures of childhood absence epilepsy and generalised seizures of juvenile myoclonic epilepsy.Lamotrigine has a wide clinical dose range and possesses favourable pharmacokinetic properties.It has a good tolerability and safety profile,which enhance compliance.Its small risk of serious skin rash should be weighed against its potential benefits when choosing lamotrigine on an individual basis.Lamotrigine is an excellent therapeutic option in epilepsy.
再问: 大哥。,你这只是摘要。我要全文的链接
再答: 你要摘要,网站要钱。 如果都不用钱,人家赚什么
Lamotrigine is an anti-epileptic agent with broad efficacy.Lamotrigine works at voltage-sensitive sodium channels,thereby stabilising the neuronal membrane and inhibiting the release of excitatory neurotransmitters such as glutamate and aspartate.Early preclinical animal studies indicate its broad-spectrum efficacy,which was later confirmed in clinical trials.Multiple randomised,placebo-controlled and comparative trials demonstrate its efficacy against partial and secondarily generalised seizures.Open-label trials show its efficacy against generalised seizures,especially absence seizures of childhood absence epilepsy and generalised seizures of juvenile myoclonic epilepsy.Lamotrigine has a wide clinical dose range and possesses favourable pharmacokinetic properties.It has a good tolerability and safety profile,which enhance compliance.Its small risk of serious skin rash should be weighed against its potential benefits when choosing lamotrigine on an individual basis.Lamotrigine is an excellent therapeutic option in epilepsy.
再问: 大哥。,你这只是摘要。我要全文的链接
再答: 你要摘要,网站要钱。 如果都不用钱,人家赚什么
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