英语翻译Deconstruction mammalian reproduction :using knockouts t
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英语翻译
Deconstruction mammalian reproduction :using knockouts to define fertility pathways
Reproduction is the sine qua non for the propagation of species and continuation of life.
It is a complex biological process that is regulated by multiple factors during the reproductive life of an organism .over the past decades ,the molecular mechanisms regulating reproduction in mammals have been rapidly unraveled by the study of a vast number of mouse gene knockouts with impaired fertility .the use of reverse genetics to generate null mutants in mice through targeted disruption of specific genes has enabled researchers to identify essential regulators of spermatogenesis and oogenesis in vivo and model human disorders affecting reproduction .this review focuses on the merits ,utility,and the variations of the knockout technology in studies of reproduction in mammals .
Deconstruction mammalian reproduction :using knockouts to define fertility pathways
Reproduction is the sine qua non for the propagation of species and continuation of life.
It is a complex biological process that is regulated by multiple factors during the reproductive life of an organism .over the past decades ,the molecular mechanisms regulating reproduction in mammals have been rapidly unraveled by the study of a vast number of mouse gene knockouts with impaired fertility .the use of reverse genetics to generate null mutants in mice through targeted disruption of specific genes has enabled researchers to identify essential regulators of spermatogenesis and oogenesis in vivo and model human disorders affecting reproduction .this review focuses on the merits ,utility,and the variations of the knockout technology in studies of reproduction in mammals .
解构哺乳动物的再生产:使用击倒定义生育力路
再生产是必要条件为种类的生活的传播和继续.
这是由多个因素调控在有机体.在再生生活期间过去十年的一个复杂生物过程,分子机制调控再生产在哺乳动物由老鼠基因击倒的一个浩大的数字的研究迅速地解开了以被削弱的生育力.对反向遗传学的用途引起空突变体在老鼠通过具体基因的被瞄准的中断使研究员辨认精子发生根本管理者并且oogenesis in vivo 和塑造人的混乱影响再生产this 回顾焦点在优点、公共事业,和击倒技术的变异在再生产的研究中在哺乳动物 (电脑译)
再生产是必要条件为种类的生活的传播和继续.
这是由多个因素调控在有机体.在再生生活期间过去十年的一个复杂生物过程,分子机制调控再生产在哺乳动物由老鼠基因击倒的一个浩大的数字的研究迅速地解开了以被削弱的生育力.对反向遗传学的用途引起空突变体在老鼠通过具体基因的被瞄准的中断使研究员辨认精子发生根本管理者并且oogenesis in vivo 和塑造人的混乱影响再生产this 回顾焦点在优点、公共事业,和击倒技术的变异在再生产的研究中在哺乳动物 (电脑译)
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